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Physiological benefits of exercise in pre-dialysis chronic kidney disease

2014Journal article Open access
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dc.contributor.authorGould, Douglas W
dc.contributor.authorGraham-Brown, Matthew PM
dc.contributor.authorWatson, Emma L
dc.contributor.authorViana, João L
dc.contributor.authorSmith, Alice C
dc.date.accessioned2021-04-28T14:36:54Z
dc.date.available2021-04-28T14:36:54Z
dc.date.issued2014
dc.description.abstractChronic kidney disease (CKD) is strongly associated with cardiovascular disease and muscle wasting, arising from numerous factors associated with declining renal function and lifestyle factors. Exercise has the ability to impact beneficially on the comorbidities associated with CKD and is accepted as an important intervention in the treatment, prevention and rehabilitation of other chronic diseases, however, the role of exercise in CKD is overlooked, with the provision of rehabilitation programmes well behind those of cardiology and respiratory services. Whilst there is now a large evidence base demonstrating the efficacy and safety of exercise training interventions in patients receiving dialysis, and this is now becoming incorporated into clinical guidelines for treatment of dialysis patients, there is a paucity of research evaluating the effectiveness of exercise in patients with CKD who are not on dialysis. Despite this, existing studies indicate that exercise can improve physical functioning and impact positively on the mediators of co-morbid diseases and upstream factors associated with progression of renal disease. Although preliminary evidence appears positive, more research is required to identify the best modes, frequency and intensities of exercise in order to optimise exercise prescription in pre-dialysis CKD patients. This review summarizes what is known about the main effects of exercise in pre-dialysis CKD patients, discusses the potential of exercise in the rehabilitation and treatment of disease and highlights the need for further research.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1111/nep.12285pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.24/1768
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectCardiovascular Diseasespt_PT
dc.subjectComorbiditypt_PT
dc.subjectDisease Progressionpt_PT
dc.subjectExercise Tolerancept_PT
dc.subjectHealth Statuspt_PT
dc.subjectHumanspt_PT
dc.subjectKidneypt_PT
dc.subjectRecovery of Functionpt_PT
dc.subjectRenal Insufficiency, Chronicpt_PT
dc.subjectRisk Assessmentpt_PT
dc.subjectRisk Factorspt_PT
dc.subjectTime Factorspt_PT
dc.subjectTreatment Outcomept_PT
dc.subjectExercise Therapypt_PT
dc.titlePhysiological benefits of exercise in pre-dialysis chronic kidney diseasept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage527pt_PT
oaire.citation.issue9pt_PT
oaire.citation.startPage519pt_PT
oaire.citation.titleNephrologypt_PT
oaire.citation.volume19pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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