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BACKGROUND: Lifting objects without knowing its weight may result in postural imbalances and be a risk factor for falls. OBJECTIVE: The aim of this study was to examine the influence of the load knowledge in postural balance when lifting different weight loads. METHODS: Thirteen male subjects (23.8 ± 3.1 years; 73.5 ± 7.8 kg; 179.1 ± 7.5 cm; foot length, 25.7 ± 1.2 cm) participated in the study. The effect of the weight overestimation on the postural stability was measured by the Index of Proximity to Stability Boundary (IPSB) and through the anterior-posterior and medio-lateral lengths displacements of the Center of Pressure (CoP). RESULTS: The results showed an increase in the IPSB when the 5 kg lifting task was performed with load knowledge. Moreover, the length of the antero-posterior and medio-lateral CoP displacement was reduced in the 5 kg lift with knowledge. CONCLUSIONS: Results showed that the lack of the loads' knowledge may lead to balance loss. Thus, when the preparation processes are not adequate, picking up similar objects with different loads may increase the risk of fall, mainly when a light weight is suddenly lifted up after a heavy one. © 2015 - IOS Press and the authors.